Monday, 30 March 2020 10:03

Biology of Coronavirus virus

Update 4/7/20:

 

 

The virus is not a living organism, but a protein molecule (DNA) covered by a protective layer of lipid (fat), which, when absorbed by the cells of the ocular, nasal or buccal mucosa, changes their genetic code, (mutation) and converts them into aggressor and multiplier cells.  

Since the virus is not a living organism but a protein molecule, it is not killed, but decays on its own. The disintegration time depends on the temperature, humidity, and type of material where it lies.  

The more confined the space, the more concentration of the virus there can be. The more open or naturally ventilated, the less.The virus is very fragile. The only thing that protects it is a thin outer layer of fat. That is why any soap or detergent is the best remedy, because the foam CUTS the FAT. So, if you rub your hands hard for 20 seconds or more, to make a lot of foam, you are dissolving the fat layer. Then, the protein molecule disperses and breaks down on its own.

 

How to “kill” coronavirus

HEAT melts fat; so, it is good to use water above 25 degrees Celsius (77 degrees fahrenheit) for washing hands, clothes and everything. In addition, hot water makes more foam and that makes it even more useful.

Alcohol or any mixture with alcohol over 65% DISSOLVES ANY FAT, especially the external lipid layer of the virus. Be sure your cleaning agent has >60% alcohol content.

Any mix with 1 part bleach and 5 parts water works because peroxide dissolves the virus protein. 

 

 

Antibiotics and COVID 19

NO BACTERICIDE will work. The virus is not a living organism like bacteria; it cannot be killed with anti-bacterial antibiotics. Scientific knowledge is being actively extended by CDC and academic university labs.

The medicine, Chloroquine, has long been used as an antimalarial and has recently been used as an antiviral drug. As an antiviral drug, it works in two ways — 1) by inhibiting virus/cell fusion by increasing pH within the initially encapsulating endosome, and 2) for viral particles that survive that initial setback, by also facilitating the intracellular transport of zinc which binds to and destroys the viral enzyme (RNA polymerase) responsible for transcribing viral RNA into DNA and co-opting the cell for its own production/reproduction.

Hydroxychloroquine ( brand name = Plaquenil) is similar in action to chloroquine with several important differences. It is more potent and has a better safety profile (less toxic) than chloroquine and is effective in suppressing the inflammatory response triggered by the body’s innate immune system. This latter effect is especially important for those who develop more severe symptoms of the virus including viral pneumonia and subsequent secondary infections such as bacterial pneumonia.

Health authorities in China and S. Korea have been using both chloroquine and hydroxychloroquine to treat COVID-19. Preliminary studies by France’s Didier Raoult suggest that combining hydroxyquinoline with Azithromycin (familiarly known as ‘Z pack’) to combat secondary bacterial pneumonia MAY have promising results in effectively reducing viral load, symptoms and contagiousness in study subjects. Some scientists think this may quickly become the treatment of choice in combatting this illness — our best hope while awaiting an effective vaccine.

 

 

Other agents

Remdesivir is an investigational intravenous drug with broad antiviral activity that inhibits viral replication through premature termination of RNA transcription and has in-vitro activity against SARS-CoV-2. This is also being fast tracked in efforts to understand its efficacy for this disease.

Lopinavir-ritonavir did not show promise for treatment of hospitalized COVID-19 patients with pneumonia in a recent clinical trial in China. This trial was underpowered, and lopinavir-ritonavir is under investigation in a World Health Organization study.

Several other drugs are under investigation in clinical trials or are being considered for clinical trials of prophylaxis or treatment of COVID-19 in the United States and worldwide. Information on registered clinical trials for COVID-19 in the United States is available at: https://clinicaltrials.gov/ct2/show/NCT04317092

 

 

(source)

Last modified on Tuesday, 22 November 2022 22:20
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